For years, Chrissy Metz had a clear reason for keeping her distance from GLP-1 medications: she wanted to understand exactly what they could do to her body before making such a personal decision. Now, the 45-year-old This Is Us actress is sharing why that position changed—and why her experience has been about far more than weight loss.

Metz, known for her Emmy-nominated performance as Kate Pearson on This Is Us, as well as appearances in The Hunting Wives and Broadway’s & Juliet, has revealed that she is now taking a GLP-1 medication after years of hesitation. She is also partnering with telehealth company Ro as a brand ambassador, with the company providing online evaluations, prescriptions and at-home delivery of treatments including GLP-1s.

A Different Health Journey:
Metz’s decision came after years of thinking carefully about her health and what would work for her. Bella Hadid has also been open about navigating a long-term health condition and the impact it has had on her life.

Why Chrissy Metz Was Skeptical About GLP-1 Medications for Years

Metz said her hesitation began roughly six years ago, around the COVID era, when GLP-1 medications were becoming a much bigger part of public conversation.

She described herself as someone who is extremely careful about understanding how substances affect the body. Initially, she assumed the medication might not work for her or could potentially bring severe side effects.

“I was very skeptical of starting a GLP-1 for a very long time. I’m talking probably six years, since really COVID, when people were sort of talking about it. I’m just very diligent about what and how things work within the body, and I’m like, ‘Oh, I don’t know what that’s gonna be like.’”
— Chrissy Metz, as reported in her August 10, 2026 interviews

That changed after a friend extensively researched GLP-1 medications and essentially presented Metz with what she described as a thesis on them.

The conversation also pushed Metz to think more seriously about her own family health history.

Another Health Chapter:
For some celebrities, taking care of their health means making changes that can affect nearly every part of their routine. Simone Biles recently shared an update about her own health after undergoing a medical procedure.

Chrissy Metz Explains Her Family History, Perimenopause and Health Concerns

Metz has spoken about obesity-related complications experienced by her father, while also acknowledging that she is now in perimenopause.

She said she had spent much of her life trying different approaches, with diets beginning as early as age 9 in some accounts. She also tried group therapy and other methods, but did not find lasting results.

Eventually, the question became less about appearance and more about longevity.

“I’m not getting any younger. I’m in perimenopause, and there were obesity issues within my family and with my father, and I felt like I’ve tried so many modalities, whether it was diets or therapy, and none of it really worked for me.”
— Chrissy Metz, as reported in August 10, 2026 coverage

After speaking with her doctor, who considered the treatment potentially beneficial, Metz decided to begin a GLP-1 through Ro.

A Separate Health Struggle:
Metz has spoken about how years of dealing with her weight shaped the way she viewed her body and health. Nate Smith has also discussed his own weight-loss journey and the changes he made along the way.

Chrissy Metz Says Her GLP-1 Journey Is About More Than Weight Loss

Metz has been especially clear that she does not view her decision as something she made simply because of outside pressure or vanity.

For her, the bigger question was how to protect her health and quality of life for the future.

“There’s so much shame around being in a bigger body, so just knowing that I wasn’t doing it purely for vanity’s sake… it was really like, ‘How can I be the healthiest for the longest? How can I really make it a priority for my future and what I want my life to look like?’”
— Chrissy Metz, as reported in August 10, 2026 coverage

She says the results have affected both her physical experience and her relationship with food.

Beyond Weight Loss:
Health stories in the spotlight are not always about weight or appearance. Baylen Dupree has shared her experience of receiving an endometriosis diagnosis after dealing with the condition herself.

The “Food Noise” Change Chrissy Metz Says Has Made the Biggest Difference

One of the most striking changes Metz has described is a reduction in what she calls “food noise”—the persistent mental preoccupation with food, meals and what she should eat next.

“It’s so nice not to be obsessing about what I’m going to have every minute, even as I’m still consuming the meal. I just vilified food for so long because I was taught that it was bad, and you shouldn’t eat this or that.”
— Chrissy Metz, as reported in August 10, 2026 coverage

According to Metz, having less mental energy consumed by those thoughts has allowed more room for creativity, being present and focusing on other parts of her life.

She has also reported reduced joint pain and inflammation, improved mobility and energy, better lab and blood work results, a more regulated menstrual cycle and greater stamina.

Those changes are particularly relevant as she performs eight shows a week as Angélique in Broadway’s & Juliet.

Her physical changes have even resulted in costume adjustments because of changes in her measurements.

Another Personal Health Story:
Metz’s openness about her health also comes as she continues working through a demanding Broadway schedule. Phil Collins has faced health problems that affected his own career and ability to perform.

How Much Weight Has Chrissy Metz Lost on GLP-1s?

Ro’s materials connected with Metz’s partnership state that she has lost 63 pounds while taking GLP-1s, after making earlier progress, pausing treatment and later continuing with the company.

That figure comes after years in which Metz had already discussed major changes to her health and fitness. She has previously spoken about losing around 100 pounds through strength training in prior years.

However, Metz says she does not want her current journey to revolve around a number on a scale.

A Different Kind of Challenge:
Mental health can be another major part of the health conversations celebrities choose to have publicly. Jace Evans’ family recently faced a difficult mental health situation that brought those struggles into the spotlight.

Why Chrissy Metz Says GLP-1s Are Not a “Magic Wand”

Metz is also stressing that medication is not a shortcut that eliminates the need for other lifestyle changes.

She has been working with a trainer on strength training and building muscle while paying closer attention to how her body feels, what she can do and how comfortable she is.

“I know it’s not a magic wand, and I need to change other things… it’s really about how comfortable I am, and learning what I’m capable of, so I really try not to have a number.”
— Chrissy Metz, as reported in August 10, 2026 coverage

She describes the broader process as a lifestyle change that requires putting herself first.

Health Can Take Many Forms:
A person’s health journey can also involve sudden setbacks rather than a long-term change. Evangeline recently faced an injury that became another closely followed personal update.

Chrissy Metz Responds to Criticism Over Her GLP-1 Decision

Metz knows the announcement is likely to attract opinions from people who have followed her career and her public discussions about weight.

She expects criticism regardless of what she does.

“Listen, when it comes to me, everybody is judgy… It doesn’t matter what I do. Before, people were like ‘Why isn’t she on a GLP-1?’ and now they’re going to know I’m on it and be like, ‘Why is she on a GLP-1?’”
— Chrissy Metz, as reported in August 10, 2026 coverage

Her response is essentially that strangers do not have access to the information behind her decision.

“They’re not in my life. They’re not in my doctor’s notes. They’re not in the hereditary issues my family has. My life is my life, and I have to do what’s best for me.”
— Chrissy Metz, as reported in August 10, 2026 coverage

She hopes being open about her experience will encourage people to research their options carefully, speak with medical professionals and make informed personal decisions without becoming paralysed by outside opinions. At the same time, she acknowledges that GLP-1 medications are not suitable for everyone.

Another Difficult Diagnosis:
Metz has emphasized making health decisions based on her own circumstances rather than outside judgment. Snooki similarly opened up after receiving a serious diagnosis and sharing details of what she was facing.

Why Ro’s Telehealth Model Fits Metz’s Broadway Schedule

Metz has also highlighted the convenience of Ro’s model. The telehealth company provides online evaluations, prescriptions and at-home medication delivery, while its care team can conduct check-ins through an app.

For someone balancing a demanding Broadway schedule, Metz says that accessibility is particularly helpful.

Ro’s other ambassadors have included Serena Williams, another high-profile figure associated with the company.

A Different Medical Journey:
Finding the right approach to a health problem can involve plenty of uncertainty before someone reaches a decision. The 80K Twins’ Kamar Williams also became the subject of concern over a mental health struggle before a later update brought some relief.

Chrissy Metz’s GLP-1 Story Is Ultimately About Her Future

Metz’s decision comes after years of hesitation, research and conversations with people she trusts, including her doctor. While her reported 63-pound loss is likely to attract attention, she has repeatedly framed the journey around much more than a figure on a scale.

Her focus is on longevity, mobility, reduced inflammation, improved energy, a quieter relationship with food and having the physical stamina to continue living and working at the level she wants.

For Metz, the GLP-1 decision represents one part of a larger attempt to make her long-term health a priority—not a claim that the medication is a universal answer.

Sources and Disclaimer

Source disclaimer: This article is based on a thorough review of reporting and information provided by People magazine, E! News, TODAY/TODAY.com, USA Today, and Ro’s company materials, including coverage and interviews published or reported on August 10, 2026. The article presents Chrissy Metz’s publicly reported statements and Ro’s partnership-related information. GLP-1 medications are prescription treatments and may not be appropriate for everyone; readers should consult a qualified healthcare professional for individual medical advice. This article is for informational purposes and should not be considered medical advice.

Sources

• People
• E! News
• TODAY / TODAY.com
• USA TODAY

Image Credit: Instagram: officialbroadwayworld and murphymade